Endocrine Abstracts

The success of islet transplantation in the treatment of type 1 diabetes has been limited by the progressive decline in islet function and viability during isolation and post transplantation. The aims of the current study were to investigate the capacity of a multifunctional progenitor cell type, mesenchymal stromal cells (MSCs), to improve islet insulin secretory function and viability after exposure to transplantation relevant stressors. Mouse islets were cultured with low (...